Respiratory Syncytial Virus Infection and Bronchiolitis

Respiratory Syncytial Virus Infection and Bronchiolitis

4. Learn the epidemiologic and experimental information suggesting the existence of a link between early-life infection with RSV and the subsequent development of recurrent wheezing and asthma in childhood and adolescence. AUTHORDISCLOSUREDr Perez has disclosed no financial relationships relevant to this article. Dr Piedimonte has disclosed he receives research grant NHLBI HL-061007 from the Na...

Immunopathogenesis of respiratory syncytial virus bronchiolitis.

BACKGROUND The objective of this study was to elucidate the relation between respiratory syncytial virus (RSV) infection and cytokine/chemokine concentrations, as well as the impact that these factors have on the severity of bronchiolitis. METHODS Children <24 months old who presented to the emergency department with clinical symptoms of bronchiolitis were prospectively enrolled in the study....

Bovine respiratory syncytial virus infection.

Bovine respiratory syncytial virus (BRSV) belongs to the pneumovirus genus within the family Paramyxoviridae and is a major cause of respiratory disease in young calves. BRSV is enveloped and contains a negative sense, single-stranded RNA genome encoding 11 proteins. The virus replicates predominantly in ciliated respiratory epithelial cells but also in type II pneumocytes. It appears to cause ...

Respiratory Syncytial Virus (RSV) Infection

Pro- and anti-inflammatory responses in respiratory syncytial virus bronchiolitis.

Respiratory syncytial virus (RSV) bronchiolitis is an important cause of severe respiratory disease in infants. This study aimed to characterise changes in pulmonary pro- and anti-inflammatory responses in infants with RSV bronchiolitis over the course of the illness. On the day of intubation (Day 1) and the day of extubation (Day X), nonbronchoscopic bronchoalveolar lavage was performed on ter...